The Warburg hypothesis and weak ELF biointeractions.

The Warburg observation concerning ATP generation in cancer cells is analyzed with regard to the likely involvement of H+ resonance effects on the angular velocity of the ATP synthase rotor. It is reasonable to expect that the variety of diseases associated with mitochondrial dysfunction may in part be related to the ATP synthase rate of rotation. Experimental measurements of ATP synthase rotational rates, as found in the literature, are consistent with what might be expected from the ion cyclotron resonance (ICR) frequencies of protons moving under a Lorentz force determined by the approximate surface intensity of the geomagnetic field (~26-65 ?T). One research approach proposes that applying the electronic sum of two critical multiple resonance frequencies simultaneously may serve to more closely resemble real world biochemical changes as compared to applying these frequencies sequentially. Accordingly, it is suggested that applying the sum of the two individual resonance frequencies corresponding to H+ and H3O+ has the capacity to both increase proton density as well as couple to ATP synthase rotation. Not only will this tend to stabilize the F0 rotational rate but also perhaps make it feasible to control this rate, thereby providing a new and potentially efficacious means of treating diseases connected to mitochondrial dysfunction electromagnetically.

Why are living things sensitive to weak magnetic fields?

There is evidence for robust interactions of weak ELF magnetic fields with biological systems. Quite apart from the difficulties attending a proper physical basis for such interactions, an equally daunting question asks why these should even occur, given the apparent lack of comparable signals in the long-term electromagnetic environment. We suggest that the biological basis is likely to be found in the weak (∼50 nT) daily swing in the geomagnetic field that results from the solar tidal force on free electrons in the upper atmosphere, a remarkably constant effect exactly in phase with the solar diurnal change. Because this magnetic change is locked into the solar-derived everyday diurnal response in living things, one can argue that it acts as a surrogate for the solar variation, and therefore plays a role in chronobiological processes. This implies that weak magnetic field interactions may have a chronodisruptive basis, homologous to the more familiar effects on the biological clock arising from sleep deprivation, phase-shift employment and light at night. It is conceivable that the widespread sensitivity of biological systems to weak ELF magnetic fields is vestigially derived from this diurnal geomagnetic effect.

Weak-field ELF magnetic interactions: Implications for biological change during paleomagnetic reversals.

Contrary to the belief that paleomagnetic reversals are not biologically significant, we find good reason to think otherwise. Attention is drawn to polarity transitions, time intervals a few thousand years long that follow the collapse of the existing geomagnetic dipole moment and precede the establishment of the new, oppositely directed moment. The geomagnetic field during transitions is reduced to a maximal mean intensity about 10% of the stable field and can exhibit low-frequency perturbations comparable to numerous laboratory-based extremely low frequency (ELF) studies reporting biological interactions, making it very likely that similar interactions must occur over the course of a polarity transition. This conclusion is strengthened by reports of medical problems that significantly correlate with intense solar winds, events that also generate ELF perturbations similar to those that can occur during polarity transitions.

Bioelectromagnetic medicine: the role of resonance signaling.

Only recently has the critical importance of electromagnetic (EM) field interactions in biology and medicine been recognized. We review the phenomenon of resonance signaling, discussing how specific frequencies modulate cellular function to restore or maintain health. The application of EM-tuned signals represents more than merely a new tool in information medicine. It can also be viewed in the larger context of EM medicine, the all-encompassing view that elevates the EM over the biochemical. The discovery by Zhadin that ultrasmall magnetic intensities are biologically significant suggests that EM signaling is endogenous to cell regulation, and consequently that the remarkable effectiveness of EM resonance treatments reflects a fundamental aspect of biological systems. The concept that organisms contain mechanisms for generating biologically useful electric signals is not new, dating back to the nineteenth century discovery of currents of injury by Matteucci. The corresponding modern-day version is that ion cyclotron resonance magnetic field combinations help regulate biological information. The next advance in medicine will be to discern and apply those EM signaling parameters acting to promote wellness, with decreasing reliance on marginal biochemical remediation and pharmaceuticals.

Electromagnetic vaccination.

Numerous reports indicate robust mitogenic responses in human lymphocytes to low-frequency electromagnetic fields. We hypothesize that these observations reflect a wider platform for immune capability than presently recognized, whereby weak electromagnetic signals play the role of antigens. This notion hinges on whether pathogenic bacteria can emit correspondingly detectable electromagnetic signals. We make this case, recalling pertinent experimental evidence by Pohl and others implicating signal emission during cell replication due to rapid electric charge redistribution. If correct, this hypothesis would also offer a new approach to the coupled problems of hospital-acquired infections and rapid adaptations to antibacterial agents, suggesting the possible treatment of patients at risk using an electromagnetic vaccination procedure. Under the reasonable assumption that signals arising from diverse bacterial varieties can be separately catalogued, prophylaxis would be achieved by prior exposure of patients to electromagnetic signatures from high-morbidity sources. Among its potential advantages such treatment would be non-invasive, inexpensive, rapidly deployed, and conceivably, less likely to lose effectiveness over time due to bacterial adaptation.

Toward an electromagnetic paradigm for biology and medicine.

Work by Lund, Burr, Becker, and others leads to the inescapable conclusion that organisms tend to express quasisystemic electric changes when perturbed, and, conversely, will tend toward wellness either through endogenous repair currents or the application of equivalent external currents. We show that an all-inclusive electromagnetic field representation for living systems is fully consistent with this extensive body of work. This electrogenomic field may provide the basis for a new paradigm in biology and medicine that is radically different from the present emphasis on molecular biology and biochemistry. An electromagnetic field description also enables a more rational transformation from the genome than the present endpoint, universally stated in terms of the so-called visible characteristics. Furthermore, once the organism is described as an electromagnetic entity, this strongly suggests the reason for the efficacy of the various electromagnetic therapies, namely as the most direct means of restoring the body's impacted electromagnetic field to its normal state.